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1975年，北京。方凌轩（郑榕 饰）大半辈子在新华医院从事中医药研究，平日里著书立说，颇有建树。作为人大代表，出席了全国四届人代会，并受到周总理的接见与关怀。会后，他加紧了冠心病新药的研制。女婿庄济生（修宗迪 饰）是四人帮在卫生部的爪牙，他对研制职业,事业,工作岗位,职责百般刁难阻挠，回到家中，方凌轩与庄济生展开面临,直面,应对,应付面交锋，他严厉斥责女婿的极左言行，恼羞成怒的庄济生通过部里四人帮的代言人，疯狂打压一切与研制新药有关的人和事。就在方凌轩感到绝望之机，周总理从医院打来电话鼓励他持续,延续,存续,连续研制，早一天服务于广大患者，这给了方凌轩及同僚,工友,伙伴,搭档极大的勇气......
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